Browsing Departament de Bioquímica i Biomedicina Molecular by Subject "615"

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Definition and validation of targets associated with the metabolic reprogramming of haematological malignancies

Contreras Mostazo, Miriam Guadalupe (Date of defense: 2020-10-21)

Cancer cells, including leukemic cells, can react to therapeutic treatment by altering their metabolic phenotype (“metabolic reprogramming”) to keep their accelerated proliferative state, eventually becoming resistant to ...

Farmacologia Molecular dels Transportadors de Nucleòsids en Teràpia del Càncer: Nucleòsids Naturals No Canònics i Ruxolitinib

Mas Marin, Eduard (Date of defense: 2021-07-23)

Nucleoside transporters are essential for nucleotide homeostasis as well as for nucleoside-derived drugs bioavailability. Non-canonical natural nucleosides or “epigenetic nucleosides” are endogenously produced and possess ...