Marin Guillen, Ines (Date of defense: 2023-04-20)
[eng] Cellular senescence is a response to stress and damage, ant it is known to activate innate immune cells. However, the mechanisms by which senescent cells interact with the adaptive arm of the ...
Meléndez Esteban, Elena (Date of defense: 2022-03-24)
The ectopic expression of transcription factors Oct4, Sox2, Klf4 and Myc (OSKM) enables the conversion of differentiated cells into pluripotent stem cells, a process known as “reprogramming”. Methods ...
Calvo Serrano, Isabel (Date of defense: 2024-02-16)
[eng] Our understanding of the transcriptional control of cellular identity is rapidly emerging. Mediator complex enriches at active enhancers, forms a protein bridge to target genes, and recruits RNA ...