Now showing items 90-109 of 3210
Jorba Argemí, Guillem (Date of defense: 2023-04-13)
El procés de descobriment i desenvolupament de fàrmacs (DDD) és costós tant econòmic com temporalment, i el qual resulta en nivells d'èxit molt reduïts. Una gran quantitat de compostos son analitzats i molts descartats en ...
Simó Riudalbas , Marc (Date of defense: 2018-07-20)
Until relatively recently, many groups of terrestrial reptiles were considered to contain only few species vastly distributed across the Arabian Peninsula. This was mostly the result of the apparent morphological uniformity ...
Schroeder, Michael Philipp (Date of defense: 2014-11-21)
Cancer is a complex disease caused by somatic alterations of the genome and epigenome in tumor cells. Increased investments and cheaper access to various technologies have built momentum for the generation of cancer genomics ...
Ibáñez Soria, David (Date of defense: 2018-09-13)
In the last decade recurrent neural networks have revolutionized the field of artificial intelligence. Their cyclic connections provide them with memory and thus with the capability of modeling processes with temporal ...
Cabús Fornas, Lluc (Date of defense: 2024-03-15)
RNA is a molecule that is released by the different tissues into the circulation. When it is found in the circulation it is called cell-free RNA (cfRNA). This type of molecule has great potential as a noninvasive biomarker ...
Llorente Lope, Carolina (Date of defense: 2020-11-27)
The main objective of this thesis is to improve understanding of citizen participation in science in Spain. Specifically, it analyses the characteristics of current participatory practices and the opinions and attitudes ...
Ferrando-Bernal, Manuel (Date of defense: 2021-07-09)
The aim of this thesis is to apply Identity by Descent (IBD) methodology to identify ancestry connections among individuals from genetically similar populations. Recombination events diminish the likelihood to detect IBDs. ...
Marchini, Marco (Date of defense: 2014-11-27)
Computational approaches for modeling expressive music performance have produced systems that emulate human expression, but few steps have been taken in the domain of ensemble performance. Polyphonic expression and ...
Morcillo Suárez, Carlos (Date of defense: 2011-12-19)
New approaches are needed to manage and analyze the enormous quantity of biological data generated by modern technologies. Existing solutions are often fragmented and uncoordinated and, thus, they require considerable ...
Muiños Gimeno, Margarita (Date of defense: 2009-12-18)
We have investigated genetic variation in microRNA-mediated regulation as a susceptibility factor for anxiety disorders following two different approaches. We first studied two isoforms of the candidate gene NTRK3 by ...
Moreno Estrada, Andrés (Date of defense: 2009-04-21)
Natural selection has played an important role in shaping human genetic variation, thus, finding variants that have been targeted by positive selection can provide insights about which genes influence human phenotypic ...
Vila-Vidal, Manel (Date of defense: 2021-09-30)
Intracranial electroencephalography (iEEG) is an invasive diagnostic procedure used in severe drug-resistant epilepsy patients that provides simultaneous recordings of multiple brain regions at a very high temporal resolution. ...
Yoshimura, Yuji (Date of defense: 2016-11-25)
The goal of this dissertation is to provide insights into spatial analysis for architecture and urban studies through examining human mobility in the built environment based on large-scale datasets. Three studies are ...
Crowell, Ciera (Date of defense: 2019-09-20)
This thesis is focused on the specific properties and evaluation of full-body interaction design of multi-user mixed reality environments to aid in intervention strategies for children with autism, to improve their ...
Vázquez Echeverría, Citlali (Date of defense: 2008-12-18)
The inner ear, the sensory organ responsible for hearing and balance, contains specialized sensory and non-sensory epithelia arranged in a highly complex threedimensional structure. To achieve this complexity, a tight ...
Capella Gutiérrez, Salvador Jesús (Date of defense: 2012-11-16)
Phylogenomics is a biological discipline which can be understood as the intersection of the fields of genomics and evolution. Its main focuses are the analyses of genomes through the evolutionary lens and the understanding ...
Lunazzi, Giulia (Date of defense: 2013-06-06)
Stimulation of Toll-like receptors (TLRs) in cells of the innate immune system activates the expression of a proinflammatory and antimicrobial gene program controlled by a network of transcriptional regulators. We show ...
Palacios Verdú, María Gabriela (Date of defense: 2015-10-19)
Williams-Beuren syndrome is a neurocognitive disorder with multisystemic manifestations of variable expressivity caused by a 1.55-1.83 Mb at chromosomal band 7q11.23. In this thesis project we have characterized the 7q11.23 ...
Fernández Puyana, David (Date of defense: 2014-05-27)
Since the inception of the United Nations in 1945 the international community has been actively engaged in the promotion and strengthening of world peace through the adoption of different peace laws and resolutions. In ...
Huerga Encabo, Hector (Date of defense: 2018-11-16)