Browsing Facultat de Química by Title

Simulación de una columna de paredes mojadas como reactor de sulfonación

Gutiérrez González, José María, 1953- (Date of defense: 1984-11-22)

Este trabajo se ha concebido como continuación de otros anteriores, realizados en el Departamento de Química Técnica de la Facultad de Química de la Universidad de Barcelona, sobre sulfonación con SO(3) vapor en reactor ...

Síntesis del fragmento 1-4 de la toxina II del escorpión "Androctonus australis hector". Estudio de la n-benzhidril-(4-brometil-3-nitro) benzoilamida como modelo monimérico del α-(4-bromometil-3-nitrobenzamido)benzilpoliestireno

Nicolás Galindo, Ernesto (Date of defense: 1988-01-01)

Como se puede comprobar por la cantidad de ejemplos que se han descrito y siguen describiéndose en la literatura, la síntesis en fase sólida se ha erigido como un método extremadamente eficaz para la obtención de péptidos ...

Síntesis y estudio de clusters de elementos metálicos con una nuclearidad máxima de cuatro

Ferrer García, Montserrat (Date of defense: 1989-01-01)

En el Departamento de Química Inorgánica de la Universidad de Barcelona se está desarrollando desde 1984 una línea de investigación que tiene como objeto la síntesis de compuestos con enlace metal-metal en la que uno de ...

Small molecules for modulating biological targets

Miret Casals, Laia (Date of defense: 2014-05-23)

CHAPTER 1: Respiratory Infectious Diseases (RID) are diseases affecting the air passages, the bronchi and the lungs. They range from acute infections, such as pneumonia and bronchitis, to chronic conditions such as ...

Sorption of perfluoroalkyl substances and Fluoroquinolone antibiotics in matrices of environmental interest

Fabregat Palau, Joel (Date of defense: 2022-09-22)

Perfluoroalkyl substances (PFASs) and fluoroquinolone antibiotics (FQs) are pollutants of environmental interest due to their widespread presence in environmental compartments and their high toxicity and disrupting effects ...

Structural characterization of amyloid beta oligomers with functional links associated to Alzheimer's disease

Puig Gomà-Camps, Eduard (Date of defense: 2019-06-20)

Alzheimer’s disease (AD) is the most common form of dementia. It was first described in 1906 by Alois Alzheimer. Later on, in 1984 George Glenner and Colin Masters isolated the amyloid-beta (Aβ) peptide from a human brain ...

Studies toward the synthesis of marine natural products Phormidolides B-D

Gil Escolano, Alejandro (Date of defense: 2018-02-16)

Marine natural products (MNPs) are, undoubtedly, highly valuable starting points for drug-development programs. Generally, MNPs show a well-defined spatial orientation that have evolved for thousands of years to interact ...

Study of the aggregation process of the amyloid beta-protein associated to Alzheimer's disease. Examination of pharmaceutically important small molecules.

Serra Vidal, Bernat (Date of defense: 2014-05-27)

Alzheimer’s disease (AD) is a neurodegenerative disorder which major risk factor is age. Current drugs only offer symptomatic alleviation in AD, thus a disease-modifying treatment is urgent. The amyloid-β (Aβ) protein ...

Study of transition metal carbide catalysts of group 5 in the RWGS reaction

Pajares Rojas, Arturo Javier (Date of defense: 2021-07-16)

Nowadays there is a growing interest in the capture and utilization of CO2 because of the increase of its concentration in the atmosphere. Captured CO2 can be recycled through different processes to obtain several value-added ...

Suspect screening of natural toxins in surface water reservoirs

Picardo, Massimo (Date of defense: 2021-02-04)

Natural toxins include a multitude of toxic secondary metabolites produced by animals, bacteria, fungi algae, and plants that are generally not intended as environmental contaminants of concern for water quality. However, ...

Syntheses of (S)-Bicalutamide and Somatostatin analogs, and development of Green procedures for Peptide synthesis

Matarín Morales, Joan Antoni (Date of defense: 2021-12-15)

Peptides are defined as compounds that contain between two and fifty amino acids connected together by amide bonds. Inside our body, peptides are natural biological messengers that play critical roles in human physiology ...

Synthesis of Sonic Hedgehog protein and development of peptide binders using phage display libraries

Palà Pujadas, Judith (Date of defense: 2018-03-12)

Chemical protein synthesis has become a potent tool for the synthesis of proteins, especially those which are not easily accessed by DNA recombinant methods, such as proteins with posttranslational modifications. The key ...

Synthesis, Biological Evaluation and Insights into the Mode of Action of Quinoxaline Containing Peptides

Zamudio Vázquez, Rubí (Date of defense: 2014-02-14)

Triostins are members of the quinoxaline antibiotic family, together with the "prototypical bisintercalator" echinomycin. These molecules display interesting antitumour activities as they inhibit transcription through ...

Targeting the disordered N-terminal domain of androgen receptor. Novel inhibitors tackling biomolecular condensation to treat late stage prostate cancer

Frigolé Vivas, Marta (Date of defense: 2020-09-23)

[eng] Drug discovery is the process by which new drugs are found and developed into the market. Given the scope of this thesis, the term “drug” will refer to small molecules and the term “target” to proteins, otherwise ...

Technical and economic evaluation of anaerobic membrane bioreactors for municipal wastewater treatment

Vinardell Cruañas, Sergi (Date of defense: 2022-05-04)

Anaerobic membrane bioreactor (AnMBR), which is a combination of membrane separation and anaerobic digestion, is an emerging biotechnology for municipal sewage treatment. The application of AnMBRs in the mainline of ...

Textiles funcionales obtenidos a partir de la incorporación de nanopartículas poliméricas

Vílchez Maldonado, Silvia (Date of defense: 2014-03-21)

El objetivo principal de la presente tesis es el diseño de nanopartículas de etilcelulosa para su utilización como vehículos de principios activos o sustancias lipofílicas y su deposición sobre un tejido, con la finalidad ...

Ti-containing hybrid organosilicas, Mo(x)C/g-C(3)N(4) nanocomposites and engineered Mo(x)C/TiO(2) nanomaterials as noble-metal-free photocatalysts for H(2) production

Wang, Yan (Date of defense: 2022-04-07)

The photocatalytic hydrogen production is considered an environmentally promising and friendly method, which could lead to achieve clean and renewable hydrogen and contribute in the future to store solar energy as chemical ...

Towards the validation of a druggable amyloid-beta oligomer as a target for Alzheimer´s disease = Cap a la validació d’un oligomer de beta-amiloide com a diana en la malaltia d’Alzheimer

Ninot Pedrosa, Martí (Date of defense: 2018-03-02)

Amyloid-beta peptide (Aβ) is strongly linked to the aetiology of Alzheimer’s disease (AD). Aβ is the main component of the amyloid plaques found in the brain of AD patients, however, Aβ is also present in the brain of ...

Tuning the composition and dimensionality of transition metal carbides as possible catalysts for green chemistry related reactions

López Berbel, Martí (Date of defense: 2023-03-03)

[eng] Transition metal carbides (TMCs) have acquired a wide potential as a green chemistry catalysts. Their relatively high abundance and their catalytic performance makes them great candidates to replace scarce and pollutant ...

Utilització de 9-fluorenilmetoxicarbonilaminoàcids a la síntesi en fase sòlida de segments peptídics protegits

Grandas Sagarra, Anna (Date of defense: 1985-07-08)

L'objectiu principal d'aquesta Tesi és posar a punt una metodologia de síntesi en fase sòlida de segments peptídics protegits, la qual cosa comporta l´engalzament successiu dels aminoàcids sobre el suport sòlid, el ...