Now showing items 12-31 of 101

    Chemical and ecotoxicological assessment of microplastics and emerging risks in the coastal environments 

    Schirinzi, Gabriella Francesca (Date of defense: 2020-06-10)

    In recent decades, global plastics production and consumption have continued to increase. Although many policy strategies on waste prevention and recycling have been implemented, much of the plastic waste is dispersed in ...

    Chemically synthesized peptide libraries as a new source of BBB-shuttles. Use of Mass Spectrometry for peptide identification and quantification 

    Guixer, Bernat (Date of defense: 2014-03-31)

    The blood-brain barrier (888) is a biological barrier that plays a crucial role protecting the brain from neurotoxic agents and regulating the influx and efflux of molecules required for the correct function of this organ. ...

    Cold Spray Deposition of WC-Co Cermets 

    Pereira de Magalhaes e Couto, Miguel (Date of defense: 2014-11-10)

    The main subject of this Thesis is the production of hard, wear and corrosion resistant cermets tungsten carbide and cobalt cermets (WC-Co) with different contents in cobalt matrix, onto low carbon steels and aluminum alloy ...

    Computational Analyses of CO2 Electroreduction and C Interactions with Transition Metals 

    Piqué Caufapé, Oriol (Date of defense: 2022-05-03)

    Catalysis is ubiquitous in chemical industries since it accelerates chemical reactions, thereby saving considerable amounts of energy. Most catalytic processes in industry are heterogeneous in nature, typically involving ...

    Computational modeling of transition metals carbides with relevant to nanotechnology and catalysis 

    Piñero Vargas, Juan José (Date of defense: 2021-12-15)

    The work carried out in this thesis is based on the study of transition metal carbides (TMCs) as catalysts study from a theoretical point of view, using the techniques of Computational Chemistry. TMC materials have been ...

    Computational Modelling of the pH Effect on Intrinsically Disordered Proteins 

    Privat Contreras, Cristian (Date of defense: 2023-04-20)

    [eng] Intrinsically disordered proteins (IDPs) landed on the molecular biology framework at the turn of the 20th century to challenge the established protein function- structure paradigm. Due to their inherent flexibility ...

    Computational modelling to study medium effect over molecules and biopolymers of interest in biomedicine 

    Barazorda Ccahuana, Haruna Luz (Date of defense: 2023-11-17)

    [eng] Computational simulation technologies facilitate the resolution of complex biomedical problems by helping researchers predict what will happen in a natural system in response to various external conditions. The main ...

    Conformational catalytic itineraries of five- and six-membered sugar rings in enzymatic and superacid media 

    Nin Hill, Alba (Date of defense: 2020-10-26)

    Carbohydrates were early considered important for energy storage and structural support for living organisms. It was not until a few decades ago that scientist discovered that they are also involved in much more complex ...

    Conjugated organic radicals and polyradicals: electronic structure and photophysics 

    Sandoval-Salinas, María Eugenia (Date of defense: 2021-02-15)

    The principal aim of this thesis is the understanding of the electronic structure of organic diradical and polyradical molecules. Unveiling the properties that give them the electronic, magnetic, and optical properties to ...

    Contaminants organoclorats, organobromats i organofosforats en població general 

    Bravo Villarraso, Natalia (Date of defense: 2019-11-21)

    Durant les dècades dels anys 50 i 60 del segle XX es van utilitzar arreu del món diferents tipus de compostos organoclorats i organobromats, que pertanyen als contaminants orgànics persistents (COPs), com a pesticides, ...

    Cosymlib: a Python library for continuous symmetry measures and its application to problems in structural chemistry 

    Bernuz Fito, Efrem (Date of defense: 2021-07-19)

    For many years symmetry has been a useful concept in the study of the spatial organization of atoms in molecules or solids. The presence of symmetry elements in a given molecular structure gives a valuable information about ...

    Crystal Engineering Studies of Squaric Acid Derivatives 

    Portell Bueso, Anna (Date of defense: 2014-11-17)

    This thesis is a multidisciplinary study of the solid state of squaric acid derivatives which combines approaches from areas such as crystal engineering, supramolecular chemistry and crystallography. The structural preferences ...

    Deciphering the role of peripheral and central nervous system metabotropic glutamate receptors in neuropathic pain with photoactivable ligands 

    Font Ingles, Joan (Date of defense: 2017-06-09)

    Pain is one of the main medical problems that in several cases results into a chronic disease with limited effective treatment, thus the discovery of new drugs to fight against constitutes a big challenge nowadays. Metabotropic ...

    Deposition of environmentally friendly cermets coatings by thermal spray techniques 

    Bazyaran, Fatemeh (Maryam) (Date of defense: 2019-04-01)

    The main objective of this research work was to produce environmentally friendly cermets coatings, Ni and Co free matrix, alternative to conventional WC- Co, by thermal spray processes. WC-Co cermets has always been one ...

    Desarrollo y caracterización del efecto doble memoria de forma obtenido mediante martensita estabilizada en aleaciones base cobre y de la fenomenología de envejecimiento 

    Fernández González, Javier (Date of defense: 1993-01-01)

    Se han obtenido distintas aleaciones policristalinas de base cobre así como monocristalinas de ZuCnAlCo, las cuales han sido caracterizadas quimícamente, estructural y calorimétricamente. Se ha utilizado un nuevo método ...

    Desarrollo y evaluación de análogos de C75 como potenciales fármacos contra la obesidad y el cáncer 

    Gómez García, Roberto (Date of defense: 2023-12-15)

    [spa] La presente Tesis de carácter multidisciplinar se centra en el diseño y síntesis de nuevos derivados de C75 como potenciales agentes antitumorales e inhibidores de la ingesta para el desarrollo de nuevos fármacos ...

    Desenvolupament i aplicació de metodologies analítiques i quimiomètriques per a l’estudi de la contaminació atmosfèrica 

    Alier Pedemonte, Marta (Date of defense: 2014-04-11)

    En aquesta Tesi s’han estudiat les fonts d’emissió de diversos contaminants atmosfèrics, principalment a l’àrea de Barcelona. Els contaminants estudiats han estat l’òxid de nitrogen (NO), compost tòxic que s’emet en grans ...

    Design and Synthesis of Bifunctional Compounds for Targeted Protein Degradation and Phosphorylation 

    Loren Parrondo, Guillem (Date of defense: 2023-09-15)

    [eng] In this doctoral thesis, the design and synthesis of bifunctional molecules that induce the degradation of a target protein in cells are described. The synthesis of molecules capable of inducing the phosphorylation ...

    Design of multifunctional polymeric nanoparticles for biomedical applications 

    Leitner, Stefanie (Date of defense: 2013-12-20)

    The general objective of this research was the design of polymeric cationic nanoparticles from nano-emulsions obtained by low-energy methods for biomedical applications. This general objective includes the preparation of ...

    Design of peptides able to modulate Protein-protein interactions (PPIs) in mutated p53 

    Nicolini, Federica (Date of defense: 2022-12-02)

    [eng] Protein-protein interactions (PPIs) play a crucial role in the homeostasis of the cells; therefore, they are important therapeutic targets. Typically, the goal in targeting PPIs is to impede them. On the contrary, ...