Characterization of mechanisms underlying neuronal survival and plasticity in Huntington's disease 

Anglada Huguet, Marta (Date of defense: 2013-07-22)

Huntington’s disease is a progressive neurodegenerative disorder caused by the expansion of a CAG tract in the exon-1 of the huntingtin gene. Mutant huntingtin induces a large amount of toxic effects that trigger cell ...