Universitat de Barcelona
Now showing items 10165-10184 of 11042
In the present thesis Supramolecular chemistry is exploited to approach applications in the area of Nanomedicine, and it is, focused on the design and preparation of different micro and nanotools for sensing and therapy, ...
[eng] The present Thesis is entitled “Synthesis and Magnetic Studies of Quasi-Isotropic Coordination Compounds with 3d and 4f cations”. The topic of the Thesis is to prepare coordination compounds of paramagnetic metal ...
[eng] My thesis was part of a collaborative project at the interface of neuropharmacology and medicinal chemistry that aimed to better understand the neuromodulation mechanisms associated with Alzheimer’s Disease (AD). In ...
Over the past decade, sphingolipids have emerged as a new class of modulators of various cell functions. Ceramide, which is the central molecule in the biosynthesis of sphingolipids and glycosphingolipids, is involved in ...
As an essential resource for life and most human activities, water resources protection have become one of the major focuses of scientific community, especially the increasing occurrence of emerging pollutants which have ...
[eng] Visible-light photocatalysis is currently one of the hottest research areas in organic chemistry, due to the possibility that offers to form C-C and C-Het bonds in a green, non-toxic and efficient way. Although ...
Dendrimers are a class of globular highly branched macromolecules with precise architecture. They consist of a multivalent surface with functional group, a core unit where branching starts, and the interior is made of ...
Esta Tesis Doctoral se presenta como Compendio de publicaciones. Los capítulos en los que se ha dividido la presente Tesis son los siguientes: Capítulo 1 – parte A: Enantioselective, Protecting Group-Free Synthesis of ...
Sphingolipids (SLs) are components of eukaryotic cell membranes that in the last 30 years have shown not only a structural role but also be involved in signaling processes and cellular responses. Therefore, the development ...
The present thesis is based on the development and optimization of a solid-phase strategy to prepare biaryl bicyclic pentapeptides. Suzuki-Miyaura cross-coupling reactions were used to obtain the biaryl bridge. The metholodogy ...
Combustion of diesel fuel in a diesel engine is a complex process where several pollutants are emitted in the engine exhausts. To solve this problem and at the same time accomplish with the increasingly stringent regulations ...
Functionalized ion-exchange resins are polymer-based materials that can be used as catalysts, in a wide variety of chemical reactions, to achieve highly selective formation of desired products at cost-effective rates. Among ...
Somatostatin, a peptidic hormone also known as somatotropin release-inhibiting factor (SRIF), is implicated in multiple biological functions, mediated by direct interaction of the peptide with a family of structurally ...
The study deals with the synthesis and biological activity of 4 different antitumours: Tetrahydro-[1,4]-dioxanisoquinolines, combretastatin A-4, dioxancarbazoles and resveratrol analogues. This study describes the synthesis ...
The synthesis of heterocyclic organic compounds allows access to a wide arsenal of compounds with potential pharmacological activity. This Thesis is part of the field of pharmaceutical chemistry, developing new therapeutic ...
Research for new antivirals to treat Influenza A virus infections has gained importance during this last decade due to the imminent danger of an Influenza pandemic. For some years, several new strains of this virus have ...
Chemical protein synthesis has become a potent tool for the synthesis of proteins, especially those which are not easily accessed by DNA recombinant methods, such as proteins with posttranslational modifications. The key ...
During this doctoral thesis, we have synthesised hundreds of grams of the TGF-β inhibitor LY2157299 (Galunisertib). This product was used by the group of Eduard Batlle in their investigations into the roles that TGF-β plays ...
Triostins are members of the quinoxaline antibiotic family, together with the "prototypical bisintercalator" echinomycin. These molecules display interesting antitumour activities as they inhibit transcription through ...
Nanoscience and Nanotechnology have become research areas that promote the design and fabrication of novel devices with a number of different applications with the aim of satisfying the growing demand of the society regarding ...
