Now showing items 2501-2520 of 11001

    Design of Catalytic Systems based on Halogen Bonding Interactions: Synthesis and Application in Catalytic Reactions 

    Martínez Bascuñana, Alba (Date of defense: 2023-09-01)

    [eng] The use of supramolecular interactions in catalysis has been widely studied and exploited for the straightforward preparation of the backbones of an array of structurally diverse stereoselective catalysts. In addition ...

    Design of Homogenous Territorial Units. A Methodological Proposal and Applications 

    Duque Cardona, Juan Carlos (Date of defense: 2004-09-30)

    The interest in geographical information technologies has grown considerably over the last three decades. Today, geographical information is no longer the exclusive domain of government and public administrations (in the ...

    Design of multifunctional polymeric nanoparticles for biomedical applications 

    Leitner, Stefanie (Date of defense: 2013-12-20)

    The general objective of this research was the design of polymeric cationic nanoparticles from nano-emulsions obtained by low-energy methods for biomedical applications. This general objective includes the preparation of ...

    Design of novel compositionally controlled hybrid and ternary nanostructures 

    Dalmases Solé, Mariona (Date of defense: 2019-02-08)

    The size/shape dependent and unique physical and chemical properties presented by nanostructured materials have attracted great attention in several fields such as energy harvesting, optoelectronics and biomedicine, among ...

    Design of peptides able to modulate Protein-protein interactions (PPIs) in mutated p53 

    Nicolini, Federica (Date of defense: 2022-12-02)

    [eng] Protein-protein interactions (PPIs) play a crucial role in the homeostasis of the cells; therefore, they are important therapeutic targets. Typically, the goal in targeting PPIs is to impede them. On the contrary, ...

    Design, characterization and applications of polyester nanoparticles obtained by enzymatic polymerization in nano-emulsions prepared by low-energy methods 

    Paulme, Camille (Date of defense: 2013-02-01)

    The presence of volatile fragrant molecules is generally associated with a feeling of pleasantness or cleanness in consumer products. Because of their high volatilities, the perception of fragrances is limited over time. ...

    Design, characterization and optimization of a novel liposomal based food supplement against chronic fatigue syndrome 

    Ruiz García, Marta (Date of defense: 2020-10-20)

    In today’s society, people’s interest against health care is growing every day. On a health- concerned population, food supplements and nutraceuticals are products with an increasing interest among the global community. ...

    Design, synthesis and biological evaluation of new polymer-drug conjugates based on polyglutamic acid and 5-Fluorouracil for the treatment of advanced colorectal cancer 

    Plà Solans, Helena (Date of defense: 2014-11-13)

    Although survival rates of colorectal cancer (CRC) treated with surgery and conventional chemotherapy are high, metastatic CRC still shows acute mortality rates. Current chemotherapeutic treatment involves high doses of ...

    Design, synthesis and biological evaluation of photoswitchable molecules targeting G protein-coupled receptors in retina 

    González Díez, Aleix (Date of defense: 2023-07-24)

    [eng] G protein-coupled-receptors (GPCRs) are the largest family of membrane proteins and mediate important cellular responses. Metabotropic glutamate receptors (mGlu) belong to the Glutamate family/Class C GPCR. These ...

    Design, synthesis and biophysical evaluation of peptides targeting pharmacologically relevant proteins 

    Guardiola Bagán, Salvador (Date of defense: 2017-09-15)

    Protein-protein interactions (PPIs) and protein surfaces are considered challenging targets for drug discovery. In this field, conventional medicinal chemistry (i.e. small molecules) has largely failed to provide effective ...

    Design, synthesis and characterisation of photoswitchable allosteric modulators of metabotropic glutamate receptors 

    Gómez Santacana, Xavier (Date of defense: 2016-05-13)

    Metabotropic glutamate receptors (mGlu receptors) are class C GPCRs widely distributed through the CNS and considered pharmacological targets for neurologic disorders, such as neuropathic pain and Parkinson’s disease, ...

    Design, synthesis and evaluation of the biological properties of colistin analogues 

    Solé Solé, Judith (Date of defense: 2022-06-03)

    Following the laws of evolution, bacteria are capable of slowly but inexorably acquiring resistance to antibiotic compounds that we have been using for decades. Therefore, bacteria that seemed harmless to most people (such ...

    Design, synthesis and study of coordination complexes for quantum computing 

    Aguilà Avilés, David (Date of defense: 2013-06-07)

    This thesis presents different strategies for the design of molecular complexes with the requirements to be used as two-qubit quantum gates. The approaches followed towards the preparation of potential qubit systems have ...

    Design, synthesis and study of coordination complexes with spin crossover or single-molecule magnet properties 

    Diego Creixenti, Rosa (Date of defense: 2022-01-21)

    Spin crossover (SCO) complexes and single-molecule magnets (SMMs) are promising prototypes that can reach magnetic bistability within the molecular scale required for data storage. Despite the extensive library of versatile ...

    Design, synthesis and study of the biological and biophysical activity of antimicrobial peptides 

    Grau Campistany, Ariadna (Date of defense: 2014-07-17)

    The global emergence and spread of multidrug-resistant bacteria is an important public health issue. However, the antimicrobial pipeline remains unacceptably lean, in fact over the last 25 years, the number of antimicrobial ...

    Design: as Organizações de Interface 

    Sá Leal, Nuno José de (Date of defense: 2017-09-14)

    O design surge, no contexto da União Europeia, associado à Inovação e, em conjugação com esta, como um forte suporte ao desenvolvimento sustentado da economia da UE e seus Estados Membros. Apesar desta postura das instituições ...

    Designing Advanced Nanocatalysts: Synthesis of complex CeO2-based Nanostructures 

    Hervés Carrete, Carmen (Date of defense: 2023-05-24)

    [eng] The main objective of this dissertation has been to stablish a bridge between materials science and its fields of application. The scope of this thesis work, under this premise, is aimed towards understanding the ...

    Desigualdad y política redistributiva: una estimación de la incidencia de los gastos sociales en España a partir de la Encuesta de Presupuestos Familiares, 1990-1991 

    Estruch Manjón, Alejandro (Date of defense: 1994-01-01)

    Uno de los hechos que están en el origen de buena parte de los conflictos sociales en la sociedad actual es la constatación de que los beneficios del crecimiento económico no se distribuyen entre todos los miembros de la ...

    Desigualdad, democracia y estado del bienestar: un análisis comparativo de los determinantes del gasto social en España (1850-2005) 

    Espuelas Barroso, Sergio (Date of defense: 2011-11-04)

    En este trabajo se construido una serie de gasto social en España, entre 1850 y 2005, que ha permitido obtener una visión de largo plazo sobre la evolución de la política social y situar la experiencia española en el ...

    Desigualdades en el acceso a los Programas Preventivos en Salud Sexual y Reproductiva. Análisis en el área de Sabadell 

    Obregón Gutiérrez, Noemí (Date of defense: 2014-01-31)

    La OMS considera desigualdades en Salud, las diferencias, injustas y evitables, entre un grupo poblacional definido social, económica, demográfica o geográficamente, relacionadas con la salud. Son el resultado de las ...