Now showing items 2495-2514 of 11001
Mas Moruno, Carlos (Date of defense: 2009-03-05)
La sepsis es un síndrome muy complejo de definir, diagnosticar y tratar. La patología de la sepsis se deriva de una respuesta perjudicial del organismo a una infección. La exposición a endotoxinas bacterianas induce una ...
Salinas Uber, Jorge (Date of defense: 2016-07-29)
One of the main objectives of this thesis was the synthesis of new chelating ligands containing a photochromic unit able to change its conformation upon light irradiation. This isomerization should serve to modify the ...
Bertran Junqué, Alexandra (Date of defense: 2018-10-25)
Matrix metalloproteinases (MMPs) are a family of zinc-containing endopeptidases involved in the degradation of the extracellular matrix. They make a major contribution to the progression of a vast number of diseases, ...
Sanllehí Figuerola, Pol (Date of defense: 2016-11-02)
Sphingolipids (SLs) are essential structural and signaling molecules of eukaryotic cells. An important group of SLs metabolites are those showing a phosphate group at the C1‒ OH. Among them, sphingosine‒1‒phosphate (S1P) ...
Águas, Sofía (Date of defense: 2009-01-01)
O:<br/><br/>O presente trabalho investiga os processos de design apropriados à eco-concepção de candeeiros de iluminação pública que possam contribuir para a sustentabilidade do espaço público urbano em geral. <br/>A ...
Vila Casadesús, Maria (Date of defense: 2017-09-05)
En esta tesis se han desarrollado e implementado distintas herramientas bioinformáticas que permiten el estudio de las interacciones miRNA-mRNA en contextos celulares específicos. oncretamente se ha creado un paquete de R ...
Martínez Bascuñana, Alba (Date of defense: 2023-09-01)
[eng] The use of supramolecular interactions in catalysis has been widely studied and exploited for the straightforward preparation of the backbones of an array of structurally diverse stereoselective catalysts. In addition ...
Duque Cardona, Juan Carlos (Date of defense: 2004-09-30)
The interest in geographical information technologies has grown considerably over the last three decades. Today, geographical information is no longer the exclusive domain of government and public administrations (in the ...
Leitner, Stefanie (Date of defense: 2013-12-20)
The general objective of this research was the design of polymeric cationic nanoparticles from nano-emulsions obtained by low-energy methods for biomedical applications. This general objective includes the preparation of ...
Dalmases Solé, Mariona (Date of defense: 2019-02-08)
The size/shape dependent and unique physical and chemical properties presented by nanostructured materials have attracted great attention in several fields such as energy harvesting, optoelectronics and biomedicine, among ...
Nicolini, Federica (Date of defense: 2022-12-02)
[eng] Protein-protein interactions (PPIs) play a crucial role in the homeostasis of the cells; therefore, they are important therapeutic targets. Typically, the goal in targeting PPIs is to impede them. On the contrary, ...
Paulme, Camille (Date of defense: 2013-02-01)
The presence of volatile fragrant molecules is generally associated with a feeling of pleasantness or cleanness in consumer products. Because of their high volatilities, the perception of fragrances is limited over time. ...
Ruiz García, Marta (Date of defense: 2020-10-20)
In today’s society, people’s interest against health care is growing every day. On a health- concerned population, food supplements and nutraceuticals are products with an increasing interest among the global community. ...
Plà Solans, Helena (Date of defense: 2014-11-13)
Although survival rates of colorectal cancer (CRC) treated with surgery and conventional chemotherapy are high, metastatic CRC still shows acute mortality rates. Current chemotherapeutic treatment involves high doses of ...
González Díez, Aleix (Date of defense: 2023-07-24)
[eng] G protein-coupled-receptors (GPCRs) are the largest family of membrane proteins and mediate important cellular responses. Metabotropic glutamate receptors (mGlu) belong to the Glutamate family/Class C GPCR. These ...
Guardiola Bagán, Salvador (Date of defense: 2017-09-15)
Protein-protein interactions (PPIs) and protein surfaces are considered challenging targets for drug discovery. In this field, conventional medicinal chemistry (i.e. small molecules) has largely failed to provide effective ...
Gómez Santacana, Xavier (Date of defense: 2016-05-13)
Metabotropic glutamate receptors (mGlu receptors) are class C GPCRs widely distributed through the CNS and considered pharmacological targets for neurologic disorders, such as neuropathic pain and Parkinson’s disease, ...
Solé Solé, Judith (Date of defense: 2022-06-03)
Following the laws of evolution, bacteria are capable of slowly but inexorably acquiring resistance to antibiotic compounds that we have been using for decades. Therefore, bacteria that seemed harmless to most people (such ...
Aguilà Avilés, David (Date of defense: 2013-06-07)
This thesis presents different strategies for the design of molecular complexes with the requirements to be used as two-qubit quantum gates. The approaches followed towards the preparation of potential qubit systems have ...
Diego Creixenti, Rosa (Date of defense: 2022-01-21)
Spin crossover (SCO) complexes and single-molecule magnets (SMMs) are promising prototypes that can reach magnetic bistability within the molecular scale required for data storage. Despite the extensive library of versatile ...