Now showing items 22-41 of 11001

    A network biology approach to breast and colorectal cancers 

    Arroyo Sánchez, Rodrigo (Date of defense: 2014-06-20)

    Network and systems biology disciplines could revolutionize the study of complex diseases by taking proteins back to their context, considering a much broader perspective of their environment without losing the molecular ...

    A network-based approach to cell metabolism: from structure to flux balances 

    Güell Riera, Oriol (Date of defense: 2015-02-12)

    The thesis called “A network-based approach to cell metabolism: from structure to flux balances” shows how the vision of cell metabolism as a whole allows to unveil new mechanisms and responses impossible to reach by ...

    A New Food Frequency Questionnaire to Assess Cocoa Consumption and its relationship with Health in University Students 

    Vicente, Filipa (Date of defense: 2016-03-09)

    Cocoa is a well recognized source of polyphenols, but studies on their consumption refer that it contributes with a low proportion to the daily polyphenol consumption. Cocoa polyphenol content is plenty recognized and the ...

    A new role for Sonic Hedgehog signalling in morphogenesis of the spinal cord = Nuevas funciones de la vía de señalización Sonic Hedgehog en la morfogénesis de la médula espinal 

    Gutiérrez Vallejo, Irene (Date of defense: 2015-12-18)

    Development of the posterior spinal cord involves secondary neurulation, a process poorly understood in which neural tube is formed by cavitation of the tail bud. Comprehension of secondary neurulation is required to ...

    A Novel Column Format for on-Chip Liquid Chromatography Fabricated in Cyclo Olefin Polymer 

    Illa Vila, Xavier (Date of defense: 2010-09-28)

    This thesis describes a novel column format to be used in pressure-driven reversed-phase liquid chromatography. The column contains an ordered pillar array where the stationary phase is supported, and it is fabricated in ...

    A novel role for glycogenin in the regulation of glycogen metabolism 

    Testoni, Giorgia (Date of defense: 2016-02-05)

    Glycogen synthesis is crucial for storing glucose residues that are released in case of energy demand. The mechanism needs to be tightly regulated because a lack or an overload of glycogen can lead to severe systemic ...

    A Novel Sensor Concept for Selective and Self-Powered Gas Detection 

    Hoffmann, Martin W. G. (Date of defense: 2015-01-19)

    Les tecnologies de sensors de gas basades en semiconductors presenten limitacions importants de selectivitat i consum d'energia. Per tant, esdevé necessari l’assaig de nous conceptes de dispositius capaços de satisfer ...

    A orillas del texto. Por una teoría del espacio paratextual narrativo 

    Caturla Viladot, Alberto (Date of defense: 2009-06-01)

    EN CASTELLANO: <br/><br/>La investigación aborda desde diferentes enfoques de la Crítica y de la Teoría Literaria el fenómeno de la partextualidad. Se hace especial hincapié en las formulaciones de la Pragmática, la Teoría ...

    A portable device for time-resolved fluorescence based on an array of CMOS SPADs with integrated microfluidics 

    Canals Gil, Joan (Date of defense: 2020-07-16)

    Traditionally, molecular analysis is performed in laboratories equipped with desktop instruments operated by specialized technicians. This paradigm has been changing in recent decades, as biosensor technology has become ...

    A produção de mobiliário urbano de fundição em Portugal: 1850 a 1920 

    Barradas, Sílvia (Date of defense: 2015-09-28)

    No século XIX, a união da arte e da indústria deu origem a uma profusão de artefactos urbanos em ferro fundido – mobiliário urbano -, dos quais a Fonte d’Art francesa se constitui como um exemplo preponderante. A difusão ...

    A proposal for the inclusion of accessibility criteria in the authoring workflow of images for scientific articles 

    Splendiani, Bruno (Date of defense: 2015-12-18)

    This thesis investigates the problem of how to provide accessible images in academic articles in the research fields of Science, Technology, Engineering and Mathematics (STEM) and in particular in biomedicine. Currently, ...

    A propòsit del «Cicle de Flo La Vigne», de Llorenç Villalonga 

    Mas Canals, Víctor de (Date of defense: 2013-01-23)

    En relació amb les novel•les de Llorenç Villalonga que integren l’anomenat Cicle de Flo la Vigne, aquesta tesi en caracteritza el context històric, analitza el concepte novel•lesc de l’autor, fa una anàlisi detallada de ...

    A Quest for Fulfillment: Lucy Pilgrim’s Map 

    Choquet, Marianne (Date of defense: 2013-07-18)

    This composite thesis is the fruit of a marriage between the creative, imaginative, and critical aspects of writing. The overall aim of its elaboration has been the creation and critical examination of an autonomous ...

    A random approach to stabilize a membrane transport protein for crystallization studies / Un enfoque aleatorio para estabilizar un transportador de membrana para estudios de cristalización 

    Rodríguez Banqueri, Arturo (Date of defense: 2013-03-14)

    X-ray crystallography is, now at days, one of the most powerful techniques to study proteins at the atomic level. Unfortunately, obtaining high quality crystals of membrane proteins for x-ray diffraction is a difficult ...

    A Study of Nanostructuring Effects on Model Heterogeneous Catalysts 

    Kozlov, Sergey (Date of defense: 2015-01-16)

    The role of heterogeneous catalysts in modern society is immense. The majority of catalysts are nanostructured solely in order to increase the fraction of atoms on their surface. The nanostructuring, however, introduces ...

    A través del espejo. Indivíduo y sociedad en la obra de Jesús Ibáñez. 

    Nacach, Pablo (Date of defense: 2001-03-23)

    Esta tesis doctoral se propone reflejar el camino recorrido por Jesús Ibáñez en su larga marcha personal, en la que se encargó no sólo de alumbrar una importante producción teórica y metodológica, sino también de participar ...

    "A ver quem passa". O Rossio. Proceso social y dinámicas interactivas en una plaza del centro de Lisboa 

    Malet Calvo, Daniel (Date of defense: 2011-10-31)

    Investigación histórica y etnográfica en el espacio simbólico y ceremonial más emblemático de la ciudad de Lisboa: O Rossio. Tratamos de agotar sus elementos físicos, relacionales y simbólicos, siguiendo varias escalas de ...

    Abatement of bisphenol analogues through ozone, hydroxyl radical and UV radiation in water: Kinetics, transformation products and toxicity 

    Porcar Santos, Oriol (Date of defense: 2024-02-02)

    [eng] Bisphenol A (BPA) has been one of the most produced chemicals during the last decades. However, as a result of its endocrine-disrupting behaviour, the use of this compound was restricted by legislation in different ...

    Aberrant TIMP-1 regulation in tumor-associated fibroblasts by the TGF-β1/SMAD3 pathway in lung cancer: implications in tumor progression and resistance to antifibrotic therapies 

    Duch Gili, Paula (Date of defense: 2022-03-14)

    Increased expression of TIMP-1 is associated with poor prognosis in virtually all cancer types, including lung cancer. However, how TIMP-1 is regulated in lung cancer and how it drives tumor progression is poorly defined. ...

    Abierto por vacaciones. Una etnografía de la apropiación turística en Lloret de Mar 

    Yanes Torrado, Sergi (Date of defense: 2016-01-15)

    Tras más de medio siglo de desarrollo de políticas fundamentadas en la producción de valor y la explotación turística del lugar, Lloret de Mar sigue siendo uno de los más destacados destinos costeros del Mediterráneo. Esta ...