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Now showing items 29243-29262 of 41711
Multiplex analysis of circRNAs in lung cancer using the nCounter technology
El càncer de pulmó (CP) és un dels càncers més comunament diagnosticats i la principal causa de mort relacionada amb el càncer a tot el món, principalment degut al seu diagnòstic en estadis tardans i a la manca de tractaments ...
Multiplex optical detection system for prosthetic joint infection diagnosis
La infección de prótesis articular (IPA) es una patología de difícil manejo terapéutico que produce tanto morbilidad física como psicológica en los pacientes afectados y, además, está asociada con un impacto económico ...
Multiplexed detection of SNPs using electrochemical melting curve analysis
L'objectiu general d'aquesta tesi doctoral és desenvolupar plataformes de geno-sensors de baix cost per a la detecció múltiple de polimorfismes d'un sol nucleòtid. La determinació de polimorfismes d'un sol nucleòtid (SNP) ...
A Multiplexed diagnostic approach for cardiovascular disease biomarkers
In the course of this thesis, the optimal epitopes for the subsequent polyclonal rabbit antibody production for cTnI and NT-proBNP have been studied and chosen. cTnI and NT-proBNP are the most relevant cardio-specific ...
Multiplicación en estado integrado y efecto protector frente a la irradiación ultravioleta del factor S de citrobacter intermedium C3
La interacción entre los hechos y las ideas ha caracterizado el continuo progreso científico de los últimos cuatro siglos. En biología esta interacción se hace aún más patente, dado que la naturaleza compleja de ...
Multiplier ideals in two-dimensional local rings with rational singularities
The aim of this memoir is to study multiplier ideals in two-dimensional local rings having at worst rational singularities. We also want to extend this study to the case of mixed multiplier ideals. The main achievements ...
Multirate mass transfer and biofilm growth modeling in porous media
Reactive transport modeling is a methodological tool to study the coupled physical, chemical and biological processes in Earth system. It is complex not only because of the nature of the equations, but also because of the ...
Multiregional sustainability at a sectoral level: Towards more effective environmental regulations
Aquesta tesi està dedicada al desenvolupament d'eines per ajudar als responsables polítics en la creació de normatives eficaces de manera eficient i metòdica. La tesi està organitzada en quatre seccions principals. A la ...
Multiresolution image segmentation based on camporend random fields: Application to image coding
La segmentación de imágenes es una técnica que tiene como finalidad dividir una imagen en un conjunto de regiones, asignando a cada objeto en la escena una o varias regiones. Para obtener una segmentación correcta, cada ...
Multiscalar strategies for the characterization of engineered P450 enzymes
Enzymes are a type of proteins that help chemical reactions happen faster in living organisms. Scientists have been able to modify these enzymes using a technique called protein engineering, which allowed to increase the ...
Multiscale behavior in living systems
This thesis focuses on the multiscale nature of the biological process that underpin the function of all living systems. A first project centers on the disease known as multiple sclerosis, and utilizes various datasets at ...
Multiscale cardiovascular analysis and simulations for the understanding of intra-uterine cardiovascular remodelling
Cardiovascular diseases are nowadays one of the major causes of death in developed countries. Besides the already known risk factors such as lifestyle and genetics, there is a growing evidence that adverse remodelling ...
Multiscale characterization of cardiac remodeling induced by intrauterine growth restriction, at organ, cellular and subcellular level
INTRODUCTION: Intrauterine growth restriction (IUGR) due to placental insufficiency affects up to 7-10% of pregnancies and is a major cause of perinatal mortality and long term morbidity. IUGR results in low birth weight, ...
Multiscale clutch models for cell mechanics
Integrin-based cell adhesion is a key mechanism in fundamental biological processes such as cell migration and wound healing, and in diseases like osteoporosis and cancer. For example, during migration, cells form adhesion ...
Multiscale environmental-ichthyoplankton assemblages relationships in the Balearic Sea
Understanding the early life stages of fishes and the processes influencing their survival has been at the heart of the fisheries oceanography since the beginning of the 20th century. By focusing on spatial and temporal ...
Multiscale image analysis of calcium dynamics in cardiac myocytes
Cardiac myocytes constitute a unique physiological system. They are the muscle cells that build up heart tissue and provide the force to pump blood by synchronously contracting at every beat. This contraction is regulated ...
Multiscale information management for historic districts' energy retrofitting : a framework, a methodology, a model
European Historic Urban Districts are highly appreciated by their inhabitants and visitors and they can be considered as one of the most valuable collective achievements of the European culture. The preservation of our ...
Multiscale materials design of hard coatings for improved fracture resistance and thermal stability
Physical vapor deposited hard coatings comprised of cubic (c) transition metal (TM)-Al-N, and (TM)-Si-N are the current work horse materials for a large number of metal cutting and wear resistant applicatíons to light ...
Multiscale mechanical and microstrutural characterization of titanium and zirconium carbonitride hard coatings
The present dissertation is an in-depth investigation from the macro to atomic scale of industrial wear-resistant CVD hard coatings deposited on cemented carbides for cutting tool applications. Micro-compression tests at ...
Multiscale Modeling of Organic Electronic Biosensor Response
[eng] There have been significant advances in organic bioelectronic devices in recent years. These devices are capable of stimulating excitable cells and can generate data to facilitate disease diagnostics and monitoring. ...
