Now showing items 22948-22967 of 41700

    Involvement of the Microtubule-Regulated RhoGEF GEF-H1 in the G12 family signaling pathways 

    Garrido Antequera, Georgina (Date of defense: 2014-09-16)

    Heterotrimeric G proteins are masters regulators of cell homeostasis. They coordinate the signaling between G protein coupled receptors (GPCRs) and their intracellular effectors. Heterotrimeric G proteins are composed of ...

    Involvement of the prefrontal cortex-limbic pathway in the development of food addiction 

    Calvé Pérez, Pablo (Date of defense: 2022-07-04)

    Food addiction is closely associated with eating disorders including obesity and binge eating. However, the neural alterations underlying this disorder have not been yet clarified. We have trained mice in an operant model ...

    Ion beam synthesis of silicon-carbon structures and related materials 

    Calvo Barrio, Lorenzo (Date of defense: 1999-07-16)

    The goal of this dissertation is the study and characterisation of high dose Carbon (C) implantation processes into Silicon (Si) and related materials for the synthesis of Silicon Carbide (SiC). The attainment of ...

    Ion binding landscapes and molecular dynamics of phospholipid membranes 

    Yang, Jing (Date of defense: 2015-12-11)

    This thesis aims at studying the physical-chemical properties of model lipid bilayers in physiological environments. Since in such conditions biological membranes composed of phospholipids and cholesterol are surrounded ...

    Ionic complexes of biodegradable polyelectrolytes 

    Tolentino Chivite, Ainhoa (Date of defense: 2014-04-29)

    Biopolymers are polymers produced by living organisms. A more broad classification would embrace also those polymers synthesized from renewable sources which are able to display biodegradability. The demand of biopolymers ...

    Ionic complexes of naturally-occurring biopolymers and cationic surfactants : a platform for industrial and biomedical applications 

    Gamarra Montes, Ana (Date of defense: 2018-07-13)

    In recent years, the increasing public concern about the environmental pollution caused by persistent plastic wastes has stimulated the interest in replacing synthetic polymers by biopolymers. The term biopolymer refers ...

    Ionic copolyesters and their nanocomposites: synthesis, characterization and properties 

    Bautista Betancur, Mayka Irina (Date of defense: 2015-09-21)

    A polymer containing small amounts of ionic groups either along the polymer backbone chains or as pendant groups is defined as ionomer. As originally proposed by Eisenberg, the interaction between ionic groups leads to the ...

    Ionic liquid-assisted the preparation of transparent cellulosic biocomposite films 

    Amini, Elahe (Date of defense: 2023-12-14)

    (English) Interest in new environmentally friendly cellulose-based products has tremendously increased in recent years. Cellulose-based composites come in various forms and have potential applications in construction, ...

    Ionic liquids with and without transition metal nanoparticles for advanced heat transfer fluids and catalysis applications. 

    Patil, Virendra Sudam (Date of defense: 2015-07-21)

    Tecnologies de transferència de calor de nova generació, amb menys consum d'energia per al benestar de la societat són necessàries. En aquest sentit, els líquids iònics (ILS) són en l'actualitat els fluids més investigats ...

    IoT@run-time: a model-based approach to support deployment and self-adaptations in IoT systems 

    Alfonso, Ivan (Date of defense: 2022-12-05)

    Today, most Internet of Things (IoT) systems leverage edge and fog computing to meet increasingly restrictive requirements and improve quality of service (QoS). Although these multi-layer architectures can improve system ...

    l'IPAD a l'àrea de música. Disseny, aplicació i anàlisi d'una propsota didàctica a l'educació primària 

    Ufartes Ollé, Gemma (Date of defense: 2016-01-29)

    La tecnologia digital ha redibuixat la manera de conviure i d’entendre el món. S’ha instaurat en el dia a dia de la majoria de llars però, segons les darreres investigacions, l’escola tot just s’inicia en l’adopció de nous ...

    iPSCs, CRISPR/Cas9 y protocolos de diferenciación basados en factores de transcripción para generar nuevos modelos neuronales y astrocíticos del síndrome de Sanfilippo 

    Benetó Gandia, Noelia (Date of defense: 2020-07-16)

    El objetivo general de esta tesis doctoral ha sido la generación de nuevos modelos celulares para el síndrome de Sanfilippo y su utilización para ensayar una aproximación terapéutica para esta enfermedad basada en el uso ...

    IRALIKU'K: La confrontación de los comunales. Etnografía e historia de las relaciones de propiedad en Goizueta 

    Montesinos Llinares, Lidia (Date of defense: 2013-12-16)

    Esta tesis, planteada inicialmente como un estudio de comunidad, presenta un estudio de caso sobre relaciones de propiedad en Goizueta; un pueblo euskaldun (vascófono) de unos 700 habitantes situado en el noroeste de ...

    IRBC-induced p53-dependent Cell Death in c-MYC-driven tumors mediated by loss of MCL1 

    Domostegui Fernández, Ana (Date of defense: 2019-12-05)

    The oncogene MYC is altered and its expression is deregulated in up to 70% of human cancers, including B cell neoplasms. Earlier studies in a mouse model of Eμ-MYC-driven B-cell lymphomas reported that oncogenic MYC relies ...

    Iridium oxide-carbon hybrid materials as electrodes for neural systems. Electrochemical synthesis and characterization 

    Carretero González, Nina Magali (Date of defense: 2014-05-23)

    El desarrollo de interfaces neuronales requiere el uso de nuevos materiales electroactivos y biocompatibles, que al aplicar campos eléctricos no causen efectos secundarios que pueden dañar los tejidos o degradar la ...

    Irlanda y la guerra civil española. Nuevas perspectivas de estudio 

    Soler Parício, Pere (Date of defense: 2013-05-11)

    Enmarcada en el estudio de la reacción internacional y la participación extranjera en la guerra civil española, esta Tesis analiza la respuesta al conflicto que se dio en Irlanda. Tal y como ocurrió en el resto de países ...

    Iron and iridium molecular complex for water oxidation catalysis 

    Codolà Duch, Zoel (Date of defense: 2014-07-11)

    Harness light from the sun is one of the 21st century’s major goals towards the substitution of fossil fuels for a renewable source of energy. Sustainable production of highly energetic molecules using sunlight as energy ...

    Iron excess and risk of type 2 diabetes mellitus in a prospective cohort of mediterranean population 

    Fernández Cao, José Cándido (Date of defense: 2016-02-15)

    Antecedents: El consum de ferro hemo i els dipòsits de ferro s'han associat amb el risc de diabetis mellitus tipus 2 (DMT2) en cohorts nord-americans, xineses, i del nord d'Europa, però aquestes relacions no han estat ...

    Iron oxide nanocubes for magnetic hyperthermia 

    Niculaes, Dina (Date of defense: 2017-04-21)

    Durant la meva tesi s’han desenvolupat tres projectes principals, centrats en l'estudi de nanosistemes basats en l'ús de nanocubs d'òxid de ferro (IONCs) per a la hipertèrmia magnètica (HM). S’ha demostrat l'ús innovador ...

    Iron Regulatory Protein/Iron Responsive Element (IRP/IRE) system: associated diseases and new target mRNAs (PPP1R1B) 

    Celma Nos, Ferran (Date of defense: 2022-05-17)

    Iron is a biometal involved in many physiological processes essential for life. Regulation of both systemic and cellular iron homeostasis is crucial for health. The IRP/IRE post-transcriptional regulatory system is in ...