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Development of new products from aquaculture fish species
Europeans are regular consumers of fish and aquaculture products. Therefore, five species of potential aquaculture rearing named: Meagre, Pikeperch, Grey Mullet, Greater Amberjack and Wreckfish were selected for new product ...
Development of new reusable materials based on Ru complexes with catalytic activity for olefin epoxidation and nitrile hydration
In this thesis we present the synthesis and characterization of different types of ruthenium complexes containing N-donor ligands together with dmso, Cl and H2O ligands, along with their complete characterization through ...
Development of new solvent-free microextraction techniques for the analysis of volatile organic compounds: application to the use of breath analysis as a toxicological tool for explosure analysis
Hippocrates predicted many years ago that breath could tell something related with our health. On his treaties, he indicated that when the body starts moving after sleeping, and breathe with more frequency, something hot ...
Development of new strategies for the synthesis of radiotracers labeled with short-lived isotopes: application to 11C and 13N
S'ha desenvolupat una nova estratègia per la síntesi ràpida i eficient de L-[metil-11C]metionina basada en el captive solvent method. La reacció de L-homocisteína (dissolució bàsica en aigua/etanol 1:1) amb [11C]CH3I en ...
Development of new strategies for the treatment of emerging opportunistic fungal infections
Aspergillus fumigatus és el fong filamentós més freqüent i, encara que normalment és sensible als antifúngics, recentment s’han detectat aïllats resistents. Neocosmospora solani, Lomentospora prolificans, Scopulariopsis ...
Development of new strategies to generate conditionally-active proteins for precision therapies
L'ús de proteïnes com a anticossos i de les citocines com a teràpia ha anat augmentant de manera constant en les últimes tres dècades. Malgrat l'èxit de les bioteràpies en el tractament de diverses malalties, aquests sovint ...
Development of new therapeutic strategies for Spinal Muscular Atrophy
L'Atròfia Muscular Espinal (AME) és una malaltia neurodegenerativa greu i la primera causa genètica de mort infantil. S'origina per la pèrdua o mutació del gen Survival Motor Neuron 1 (SMN1) que causa una deficiència de ...
Development of new tools for local electron distribution analysis
This thesis focuses in the development and application of new tools for the analysis of the electron distribution in molecules, focusing on the concepts of local spins, and oxidation state. The thesis can be divided into ...
Development of New Tools for the Synthesis of "Difficult Peptides"
The known as "difficult peptides", as well as those sequences that aggregate in solution, are some of those molecules with high applicability as nanomaterials or even in medicine field. This thesis has addressed to overcome ...
Development of new transition metal complexes for their use in sustainable catalytic processes and as antitumoral agents
In this thesis we present the synthesis and characterization of different types of ruthenium complexes containing N-donor ligands together with monodentate ligands, along with their complete characterization through s ...
The development of new, direct and asymmetric Ni(II) catalysed carbon-carbon bond forming reactions and their application to total synthesis
This thesis focuses on the search for new methodologies for the direct, stereoselective and catalytic formation of carbon-carbon bonds through the formation of chiral nickel(II) enolate species and the application of such ...
Development of new, non-invasive tools based on faecal bacterial signatures for the early detection of colorectal cancer
This thesis aims to develop a new non-invasive tool based on faecal bacterial markers for the early detection of colorectal cancer, which is capable of detecting precancerous lesions before the onset of clinical signs. ...
Development of nonlinear techniques based on time-frequency representation and information theory for the analysis of EEG signals to assess different states of consciousness
Electroencephalogram (EEG) recordings provide insight into the changes in brain activity associated with various states of anesthesia, epilepsy, brain attentiveness, sleep disorders, brain disorders, etc. EEG's are complex ...
Development of novel and multifunctional polymeric nanoparticles for brain targeted drug delivery
Controlled release systems have become an innovative technique to treat diseases like cancer by the targeted delivery to individual cells and tissues. There is an urgent need to achieve efficacious and safe delivery with ...
Development of novel biobased thermoplastic polyurethanes containing 2,5-furandicarboxylic acid polyesters
Aquesta tesi doctoral descriu la síntesi i caracterització d’una nova família de biopoliuretans termoplàstics basats en polièsters d’àcid 2,5-furandicarboxílic, amb l’objectiu de produir materials amb una baixa empremta ...
Development of novel bioinks formulations based on supramolecular self-assembled hydrogels for tissue regeneration.
The field of tissue engineering relies on the use of biomaterials as scaffolds for tissue and organ regeneration. If properly designed, these scaffolds can mimic the in vivo microenvironment while also providing initial ...
Development of novel catalytic materials for removal of emerging organic pollutants by advanced oxidation processes (AOPS)
L'objectiu principal del nostre treball és el desenvolupament de nous materials catalítics i mètodes prometedors, eficients i respectuosos amb el medi ambient, per la degradació i la mineralització de contaminants orgànics ...
Development of novel EELS methods to unveil nanoparticle properties
[eng] The aim of this thesis has been two-fold. First, to develop new processing and analysis tools and strategies for extracting information from EELS data, and second, to apply the methods to different nanoparticle systems ...
Development of novel electroactive nanofluids for flow cells
Flow cells are on their way to become a key player for electrical energy storage (EES) thanks to their suitability as load-levelling devices thus contributing to the development of smart grid and to offset the intermittency ...
Development of novel electrochemical and optical Lab-on-a-chip platforms for contaminants and biomarkers sensing
La detección de contaminantes peligrosos requiere especial atención debido a su posible toxicidad, baja concentración en muestras reales y, en la mayoría de los casos, una imposibilidad de llevar a cabo la detección a ...
